Selected Publications

​For a full list of publications please go to: PubMed and Google Scholar

(*co-first author, # co-corresponding author)

2022

Characterizing cis-regulatory elements using single-cell epigenomics

Preissl S#, Gaulton KJ#, Ren B#

Nature Review Genetics 2022 

Paper|PubMed

2021

A single-cell atlas of chromatin accessibility in the human genome.

Zhang K, Hocker JD, Miller M, Hou X, Chiou J, Poirion OB, Qiu Y, Li YE, Gaulton KJ, Wang A, Preissl S, Ren B

Cell 2021 

Paper|PubMed|Data

An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum.

Li YE*, Preissl S*, Hou X, Zhang Z, Zhang K, Fang R, Qiu Y, Poirion OB, Li B, Liu H, Wang, Han JY, Lucero J, Yan Y, Kuan S, Gorkin DU, Nunn M, Mukamel EA, Behrens MM, Ecker JRE, Ren B

Nature 2021

Paper|PubMed|Data

Cardiac Cell Type-Specific Gene Regulatory Programs and Disease Risk Association.

​Hocker JD, Poirion OB, Zhu F, Buchanan J, Zhang K, Chiou J, Wang T, Zhang Q, Hou X, Li YE, Zhang Y, Farah EN, Wang A, McCulloch AD, Gaulton KJ, Ren B#, Chi NC#, Preissl S#

Science Advances 2021 

Paper|PubMed|Data

2020

Single-cell multiomic profiling of human lungs reveals cell-typespecific and age-dynamic control of SARS-CoV2 host genes.

Wang A#, Chiou J, Poirion OB, Buchanan J, Valdez MJ, Verheyden JM, Hou X, Kudtarkar P, Narendra S, Newsome JM, Guo M, Faddah DA, Zhang K, Young RE, Barr J, Sajti E, Misra R, Huyck H, Rogers L, Poole C, Whitsett JA, Pryhuber G, Xu Y, Gaulton KJ#, Preissl S#, Sun X#; NHLBI LungMap Consortium

Elife 2020

Paper|PubMed|Data

2019

Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells.

Zhang Y*, Li T*, Preissl S*, Amaral ML, Grinstein JD, Farah EN, Destici E, Qiu Y, Hu R, Lee AY, Chee S, Ma K, Ye Z, Zhu Q, Huang H, Fang R, Yu L, Izpisua Belmonte JC, Wu J, Evans SM, Chi NC, Ren B

Nature Genetics 2019

Paper|PubMed

2018

Single nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell type- specific transcriptional regulation.

Preissl S*, Fang R*, Huang H, Zhao Y, Raviram R, Gorkin DU, Zhang Y, Sos BC, Afzal V, Dickel DE, Kuan S, Visel S, Pennacchio LA, Zhang K, Ren B

Nature Neuroscience 2018

Paper|PubMed

2015

Deciphering the Epigenetic Code of Cardiac Myocyte Transcription.

Preissl S, Schwaderer M, Raulf A, Hesse M, Grüning BA, Köbele C, Backofen R, Fleischmann BK, Hein L, Gilsbach R

Circulation Research 2015

Paper|PubMed

2014

Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.

Gilsbach R*, Preissl S*, Grüning BA, Schnick T, Burger L, Benes V, Würch A, Bönisch U, Günther S, Backofen R, Fleischmann BK, Schübeler D, Hein L

Nature Communications 2014

Paper|PubMed