Selected Publications
For a full list of publications please go to: PubMed and Google Scholar
(*co-first author, # co-corresponding author)
2023
Single-cell analysis of chromatin accessibility in the adult mouse brain.
Zu S*, Li YE*, Wang K*, Armand EJ, Mamde S, Amaral ML, Wang Y, Chu A, Xie Y, Miller M, Xu J, Wang Z, Zhang K, Jia B, Hou X, Lin L, Yang Q, Lee S, Li B, Kuan S, Liu H, Zhou J, Pinto-Duarte A, Lucero J, Osteen J, Nunn M, Smith KA, Tasic B, Yao Z, Zeng H, Wang Z, Shang J, Behrens MM, Ecker JR, Wang A, Preissl S, Ren B.
Nature 2023
A comparative atlas of single-cell chromatin accessibility in the human brain
Li YE, Preissl S, Miller M, Johnson ND, Wang Z, Jiao H, Zhu C, Wang Z, Xie Y, Poirion OB, Kern C, Pinto-Duarte A, Tian W, Siletti K, Emerson N, Osteen J, Lucero J, Lin L, Yang Q, Zhu Q, Zemke N, Espinoza S, Yanny AM, Nyhus J, Dee N, Casper T, Shapovalova N, Hirschstein D, Hodge RD, Linnarsson S, Bakken T, Levi B, Keene CK, Shang J, Lein E, Wang A, Behrens MM, Ecker JR, Ren B
Science 2023
Wang G*, Chiou J*, Zeng C*, Miller M, Matta I, Han JY, Kadakia N, Okino ML, Beebe E, Mallick M, Camunas-Soler J, Dos Santos T, Dai XQ, Ellis C, Hang Y, Kim SK, MacDonald PE, Kandeel FR, Preissl S#, Gaulton KJ#, Sander M#.
Nature Genetics 2023
Interpreting non-coding disease-associated human variants using single-cell epigenomics.
Gaulton KJ#, Preissl S#, Ren B#
Nature Review Genetics 2023. Review
Characterizing cis-regulatory elements using single-cell epigenomics
Preissl S#, Gaulton KJ#, Ren B#
Nature Review Genetics 2023. Epub 2022. Review
2021
A single-cell atlas of chromatin accessibility in the human genome.
Zhang K*, Hocker JD*, Miller M, Hou X, Chiou J, Poirion OB, Qiu Y, Li YE, Gaulton KJ, Wang A, Preissl S, Ren B
Cell 2021
An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum.
Li YE*, Preissl S*, Hou X, Zhang Z, Zhang K, Fang R, Qiu Y, Poirion OB, Li B, Liu H, Wang, Han JY, Lucero J, Yan Y, Kuan S, Gorkin DU, Nunn M, Mukamel EA, Behrens MM, Ecker JRE, Ren B
Nature 2021
Cardiac Cell Type-Specific Gene Regulatory Programs and Disease Risk Association.
Hocker JD, Poirion OB, Zhu F, Buchanan J, Zhang K, Chiou J, Wang T, Zhang Q, Hou X, Li YE, Zhang Y, Farah EN, Wang A, McCulloch AD, Gaulton KJ, Ren B#, Chi NC#, Preissl S#
Science Advances 2021
2020
Single-cell multiomic profiling of human lungs reveals cell-typespecific and age-dynamic control of SARS-CoV2 host genes.
Wang A*#, Chiou J*, Poirion OB*, Buchanan J*, Valdez MJ*, Verheyden JM, Hou X, Kudtarkar P, Narendra S, Newsome JM, Guo M, Faddah DA, Zhang K, Young RE, Barr J, Sajti E, Misra R, Huyck H, Rogers L, Poole C, Whitsett JA, Pryhuber G, Xu Y, Gaulton KJ#, Preissl S#, Sun X#; NHLBI LungMap Consortium
Elife 2020
2019
Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells.
Zhang Y*, Li T*, Preissl S*, Amaral ML, Grinstein JD, Farah EN, Destici E, Qiu Y, Hu R, Lee AY, Chee S, Ma K, Ye Z, Zhu Q, Huang H, Fang R, Yu L, Izpisua Belmonte JC, Wu J, Evans SM, Chi NC, Ren B
Nature Genetics 2019
2018
Single nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell type- specific transcriptional regulation.
Preissl S*, Fang R*, Huang H, Zhao Y, Raviram R, Gorkin DU, Zhang Y, Sos BC, Afzal V, Dickel DE, Kuan S, Visel S, Pennacchio LA, Zhang K, Ren B
Nature Neuroscience 2018
2015
Deciphering the Epigenetic Code of Cardiac Myocyte Transcription.
Preissl S, Schwaderer M, Raulf A, Hesse M, Grüning BA, Köbele C, Backofen R, Fleischmann BK, Hein L, Gilsbach R
Circulation Research 2015
2014
Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.
Gilsbach R*, Preissl S*, Grüning BA, Schnick T, Burger L, Benes V, Würch A, Bönisch U, Günther S, Backofen R, Fleischmann BK, Schübeler D, Hein L
Nature Communications 2014